Dr. K. Lance Gould, McGovern Medical School, University of Texas Health Science Center

Project Overview

The Brockman Foundation Medical Research Grant Program has provided support for two research projects being conducted by Dr. K. Lance Gould and his teams at McGovern Medical School at the University of Texas Health Science Center in Houston.

Dr. Gould is the Martin Bucksbaum Distinguished University Chair, Professor of Cardiovascular Medicine, and Executive Director of the Weatherhead P.E.T. Center for Preventing and Reversing Atherosclerosis at McGovern.

Brockman Foundation funding supports the continuation of a research project by Dr. Gould and his team that seeks to establish scientific, evidence-based protocols for changing cardiology practice and patient dietary and lifestyle behaviours toward improving outcomes of patients with high-risk coronary artery disease.

In addition, grant support by the Brockman Foundation Medical Research Grant Program has facilitated the development by Dr. Gould and his team of HeartSee software. The software incorporates and integrates the concepts, discoveries, experience and cumulative data acquired over 45 years into an easily-understood, visual graphic display for identifying or quantifying early or advanced coronary artery disease to guide its management by medical–lifestyle treatment, with stents, and with bypass surgery only when essential to prevent heart attack.

Over the past 45 years, Dr. Gould’s research established the foundations for current imaging of coronary artery disease now used worldwide including the concepts of Coronary Flow Reserve, pharmacologic stress imaging of coronary blood flow, the quantitative analysis of the coronary angiogram, cardiac positron emission tomography, fractional flow reserve at coronary angiogram for guiding stents, physiologic severity of coronary disease to guide stents or bypass surgery, and prevention or reversal of coronary atherosclerosis by comprehensive pharmacologic treatment and healthy living.

Recent research by Dr. Gould and his team provides important insights and partial explanation for the different manifestations of coronary artery disease in women as compared to men.

Project Highlights

  • Overview: Research Project, and HeartSee software